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Programming Aug 8, 2024 10 min read

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The bro split has you training chest once a week. Full body programs hit it three times. Social media influencers claim daily training is the secret. Who's right? The research has a clear answer—and it's probably not what your gym buddy told you.

Training frequency—how often you train each muscle group per week—directly impacts muscle growth. Get it right and you maximize your time in the gym. Get it wrong and you either leave gains on the table or dig yourself into an overtraining hole.

The Frequency Debate

For decades, bodybuilding culture promoted the "bro split"—one muscle group per day, once per week. Chest Monday, back Tuesday, legs Wednesday, and so on. The logic: destroy a muscle with high volume, then give it a full week to recover and grow.

But research from the last 15 years tells a different story. The problem with once-per-week training isn't that it doesn't work—it's that it's not optimal for most lifters.

The Case Against Once Per Week

  • Protein synthesis window: Elevated muscle protein synthesis lasts 24-48 hours after training, not 7 days
  • Diminishing returns: After a certain point, more sets in one session don't produce more growth
  • Excessive fatigue: Cramming 15-20 sets into one session creates more fatigue than spreading it across two
  • Skill acquisition: More frequent practice improves movement patterns faster

What the Research Says

A landmark 2016 meta-analysis by Schoenfeld et al. compared training frequencies while controlling for total weekly volume. The findings were clear:

Key Finding

Training each muscle group 2x per week produced significantly greater hypertrophy than 1x per week (effect size: 0.25). Training 3x per week showed a trend toward additional benefit but wasn't statistically significant.

The takeaway: when total weekly volume is equal, spreading that volume across two sessions beats cramming it into one.

Why 2x Per Week Works

  • Multiple protein synthesis peaks: Two training sessions = two MPS elevations per week
  • Better volume tolerance: 8 sets on Monday and 8 on Thursday is more productive than 16 sets on Monday
  • Improved recovery: Lower per-session fatigue allows higher quality training
  • Consistent practice: More exposure to movement patterns accelerates skill development

Understanding Muscle Protein Synthesis

Muscle growth happens when muscle protein synthesis (MPS) exceeds muscle protein breakdown. Training elevates MPS, but this elevation is temporary.

The MPS Timeline

  • 0-4 hours post-training: MPS begins to rise
  • 24-36 hours: MPS peaks
  • 36-48 hours: MPS returns toward baseline
  • 48-72 hours: MPS back to baseline for most lifters

This timeline explains why once-per-week training is suboptimal. If you train chest on Monday, MPS is elevated through Wednesday at most. Thursday through Sunday, your chest is essentially in maintenance mode—no elevated growth signal.

Train chest on Monday AND Thursday, and you get two MPS elevations per week instead of one. More growth signal, more growth.

Practical Implication

Space your sessions for each muscle group 48-72 hours apart. This allows MPS to return to baseline before the next elevation, maximizing total growth stimulus per week.

Optimal Frequency by Muscle Group

Not all muscles are created equal. Smaller muscles with faster recovery can handle higher frequencies:

Muscle Group Optimal Frequency Reason
Calves 3-6x/week Small muscle, fast recovery, stubborn growth
Abs 3-5x/week Small muscle, recovers quickly
Side/Rear Delts 3-4x/week Small muscles, minimal systemic fatigue
Biceps 2-3x/week Small muscle, moderate recovery needs
Triceps 2-3x/week Gets indirect work from pressing
Chest 2x/week Medium recovery needs
Back 2x/week Large muscle group, moderate recovery
Shoulders (Front) 1-2x/week Gets heavy indirect work from pressing
Quads 2x/week Large muscle, significant systemic fatigue
Hamstrings 2x/week Moderate recovery needs
Glutes 2x/week Gets indirect work from compounds

Training Splits and Their Frequencies

Your training split determines your per-muscle frequency. Here's how popular splits compare:

Full Body (3x/week)

Example: Mon-Wed-Fri, train all muscles each session

  • Frequency: 3x/week per muscle
  • Pros: High frequency, great for beginners, flexible scheduling
  • Cons: Sessions get long, hard to hit high volume per muscle
  • Best for: Beginners, time-limited lifters

Upper/Lower (4x/week)

Example: Mon-Tue-Thu-Fri (upper-lower-upper-lower)

  • Frequency: 2x/week per muscle
  • Pros: Optimal frequency, balanced workload, manageable sessions
  • Cons: Requires 4 gym days
  • Best for: Intermediates, most lifters

Push/Pull/Legs (6x/week)

Example: 6 days on, 1 day off (PPL-PPL-rest)

  • Frequency: 2x/week per muscle
  • Pros: High volume capacity, targeted sessions
  • Cons: Requires 6 gym days, higher fatigue
  • Best for: Advanced lifters with time

Bro Split (5-6x/week)

Example: Chest-Back-Shoulders-Arms-Legs

  • Frequency: 1x/week per muscle
  • Pros: Simple, high volume per session
  • Cons: Suboptimal frequency, excessive per-session fatigue
  • Best for: Those who enjoy it (suboptimal but works)
Split Days/Week Frequency Best For
Full Body 3 3x/muscle Beginners, busy schedules
Upper/Lower 4 2x/muscle Most lifters (recommended)
PPL (1x) 3 1x/muscle Maintenance phases
PPL (2x) 6 2x/muscle Advanced, high volume
Bro Split 5-6 1x/muscle Preference-based

Frequency Recommendations by Experience Level

Beginners (0-1 year)

Higher frequency works well because you're using lighter weights and recovering faster. You also benefit from more practice with movement patterns.

  • Recommended frequency: 2-3x per muscle per week
  • Best splits: Full body (3x), Upper/Lower (4x)
  • Volume per session: 3-4 sets per muscle group

Intermediates (1-3 years)

You're lifting heavier and creating more fatigue per session. Recovery becomes more important.

  • Recommended frequency: 2x per muscle per week
  • Best splits: Upper/Lower (4x), PPL (6x)
  • Volume per session: 4-6 sets per muscle group

Advanced (3+ years)

High training loads require more recovery. You may need to reduce frequency or periodize it.

  • Recommended frequency: 1.5-2x per muscle per week
  • Best splits: PPL (6x), specialized splits
  • Volume per session: 5-8 sets per muscle group

Practical Implementation

1

Choose a Split That Fits Your Schedule

The best frequency is the one you can sustain. If you can only train 3 days per week, full body beats a half-completed PPL split.

2

Aim for 2x Per Week Per Muscle

This is the evidence-based sweet spot for most lifters. Structure your split to hit each muscle twice weekly.

3

Space Sessions 48-72 Hours Apart

If you train chest Monday, train it again Thursday or Friday—not Tuesday. This allows adequate recovery while keeping frequency high.

4

Distribute Volume Evenly

If your weekly chest volume is 16 sets, do 8 sets per session across two days—not 12 and 4. Even distribution maximizes each session's productivity.

5

Increase Frequency for Lagging Parts

Weak points often respond to higher frequency. If your calves won't grow, try training them 4-6x per week with moderate volume each session.

Frequently Asked Questions

How many times per week should I train each muscle group?

For most lifters, 2x per week is optimal for hypertrophy. This frequency allows you to spread weekly volume across multiple sessions while providing enough recovery time. Research shows 2x per week beats 1x per week when total volume is equal.

Is training a muscle once a week enough?

You can build muscle training once per week, but it's suboptimal. Studies show 2x per week produces approximately 3.1% more muscle growth. The bro split works but requires very high per-session volume, which creates more fatigue and limits total weekly volume.

Can I train the same muscle every day?

Training large muscle groups daily isn't recommended due to inadequate recovery. However, small muscles like calves, abs, and rear delts can handle daily training with appropriate volume. For most muscles, 48-72 hours between sessions is ideal.

What is the best workout split?

Upper/Lower (4 days) and Push/Pull/Legs (5-6 days) naturally achieve 2x per week frequency. The best split is one that fits your schedule consistently. Choose based on how many days you can reliably train.

Should beginners train more or less frequently?

Beginners can train each muscle 2-3x per week because they use lighter weights and recover faster. They also benefit from more movement practice. As you advance and lift heavier, you may need to reduce frequency to allow adequate recovery.

References

  1. Schoenfeld BJ, et al. Effects of Resistance Training Frequency on Measures of Muscle Hypertrophy. Sports Med. 2016;46(11):1689-1697. PubMed
  2. Dankel SJ, et al. Frequency: The Overlooked Resistance Training Variable for Inducing Muscle Hypertrophy? Sports Med. 2017;47(5):799-805. PubMed
  3. Grgic J, et al. Effect of Resistance Training Frequency on Gains in Muscular Strength. Sports Med. 2018;48(5):1207-1220. PubMed
  4. Ralston GW, et al. The Effect of Weekly Set Volume on Strength Gain. Sports Med. 2017;47(12):2585-2601. PubMed
  5. Damas F, et al. The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis. Eur J Appl Physiol. 2018;118(3):485-500. PubMed
  6. MacDougall JD, et al. Muscle protein synthesis following resistance exercise in humans. J Appl Physiol. 1995;78(4):1454-60. PubMed

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